Fusion inhibitors are a new class of drugs that act against HIV; they got that name because they prevent the virus from fusing with the inside of a cell and so stop it from replicating. Though this term has been used in the pharmaceutical industry since the mid-1990s, it has only very recently started to be seen in the non-specialist press because the first example, Fuzeon (generic name enfuvirtide), was approved by the US Food and Drug Administration only in 2003. Such drugs are members of a broader class, the entry inhibitors, which stop the virus from entering the cell in the first place. These are classed as antiretroviral drugs, like other HIV agents, since HIV is a retrovirus, one that works by generating a DNA copy of its RNA genome inside the cell, the reverse of normal genetic replication, which goes from DNA to RNA.
Search World Wide Words
Recently added or updated
Not my pigeon; Subnivean; Black as Newgate knocker; Boxing Day; Chalazion; Fizgig; Spin a yarn; What am I? Chopped liver?; Happy as a sandboy; Tomfoolery; Fair to middling; So help me Hannah; Joe Soap; Nimrod; Isabelline; No soap; Umquhile; Steal one’s thunder; Katy bar the door; Simoleon.
Support World Wide Words!
Donate via PayPal. Select your currency from the list and click Donate.